12:30-13:30
By invitation, EBPS Full Committee members
14:00-14:15
Welcome remarks [at Rittersaal, 1st floor]
14:15-15:00
Plenary 1: Distinguished Investigator Award lecture
Pier Vincenzo Piazza (France)
Signaling Specific inhibitors of the CB1 receptor (CB1-SSi), a new pharmacological class to treat pathological states related to a hyperactivity of the cannabinoid system
15:15-16:45
Travel Awardee Data Blitz [at Rittersaal, 1st floor]
16:45-17:15
Break and mentor-mentee meeting
17:15-18:15
Panel Discussion: Equity Diversity & Inclusion at EBPS and beyond [at Rittersaal, 1st floor]
Moderators: Shelly Flagel (US) and Marco Venniro (US)
Panelists: Brianna George (US), Leah Mayo (Canada), Margarita Moreno (Spain), Mark Namba (US), Ipek Yalcin (France)
Submit discussion questions for the panelists ahead of the meeting here
18:15-21:00
Opening reception
8:30-9:15
Plenary lecture 2 [at Aula]
Rohini Kuner (Germany)
Cortico-limbic-striatal circuitry in chronic pain
9:30-11:00
Parallel symposia
Symposium 1 • Development and clinical translation of novel pharmacotherapies for substance use disorders [at Aula]
Chair: Nicholas Everett (Australia)
Michael Bowen (Australia)
KNX100: a novel clinical-stage small molecule being developed for the treatment of opioid withdrawal
Nurulain Zaveri (US)
Challenges in preclinical to clinical translation of a new molecular entity at a novel pharmacological target for smoking cessation and relapse prevention
Erica Young (US)
Nonmuscle myosin IIB as a therapeutic target for methamphetamine addiction
Markus Heilig (Sweden)
Targeting GABA-B receptors for alcohol addiction: from rats to humans
Symposium 2 • Translational insights on social support and substance use disorders [at Manfred-Lautenschläger-Hörsal]
Chair: Marco Venniro (US) & Irene Perini (Sweden)
Debra Bangasser (US)
The effect of early resource scarcity on social motivation
Ingrid Reverte (Italy)
Glutamate receptor plasticity in the nucleus accumbens core after social choice-induced voluntary abstinence
Irene Perini (Sweden)
Harmful behaviors and social processing
Xiaosi Gu (US)
Social controllability: implication for computational addiction neuroscience
Symposium 3 • Divergent claustrum projection networks support different cognitive and behavioral roles [at Fuchs-Petrolub-Festsaal]
Chair: Ami Citri (Israel)
Roberto de la Torre Martinez (Sweden)
Claustrum projections to the anterior cingulate cortex are layer and cell-type dependent
Solange Brown (US)
Motor signals in the mouse claustrum in a cross-modal sensory selection task
Ami Citri (Israel)
Claustral neurons projecting to frontal cortex limit opioid consumption
Ida Fredriksson (US)
The role of projections from claustrum to ventral subiculum in incubation of opioid craving after voluntary abstinence
11:00-11:30
Coffee break [at Katakomben]
11:30-13:00
Parallel symposia
Symposium 4 • A translational perspective on opioid modulation of fear learning [at Fuchs-Petrolub-Festsaal]
Chair: Isabell Meier (Norway)
Joanna Yau (Australia)
Opiods and aversive prediction error
Jan Haaker (Germany)
Opioidergic regulation of social observational threat learning
Isabell Meier (Norway)
Endogenous opioid modulation of safety learning
Guro Løseth (Norway)
Beyond analgesia: opioid effects and mechanisms across domains
Symposium 5 • The impacts of early life adversity on adult stress and reward behaviours: leveraging animal and human studies to inform novel treatments [at Manfred-Lautenschläger-Hörsal]
Chair: Molly Carlyle (Norway)
Tallie Z. Baram (US)
Novel stress-sensitive brain projections mediate the impact of early-life adversity on adult reward behaviors
Molly Carlyle (Norway)
Altered subjective drug reward after early life adversity in humans
Sophia Levis (US)
Sex-specific circuit mechanisms of disordered reward-seeking caused by early life adversity
Christine Heim (Germany)
Neurobiological consequences of early-life stress: from mechanisms to novel approaches for the developmental programming of lifelong health
Symposium 6 • Preclinical and clinical insights into psychedelics and how to study them [at Aula]
Chair: Charles Bradberry (US)
Alejandro Torrado Pacheco (US)
Acute psilocybin enhances cognitive flexibility in rats
Melissa Herman (US)
Sex-specific effects of psychedelic drug exposure on central amygdala reactivity and behavioral responding
Patrick Fisher (Denmark)
Multimodal clinical imaging of psychedelics
Sandeep Nayak (US)
The unique nature of psychedelic therapy, the challenges that come with studying it, and some ways to address them
13:00-15:00
Lunch and Posters [at Katakomben]
15:00-16:30
Parallel symposia
Symposium 7 • Social transfer of negative emotion: from circuits to behaviour [at Aula]
Chair: Rachel Moloney (Ireland)
Rachel Moloney (Ireland)
“I Feel Your Pain”: understanding socially transmitted pain in a novel rat model
Francesco Papaleo (Italy)
Self-experience impact on emotion discrimination is modulated by prefrontal corticotropin-releasing factor
Ewelina Knapska (Poland)
Coding of own and others' emotional expressions in rat prefrontal cortex
Andrew Holmes (US)
A distinct cortical code for socially learned threat
Symposium 8 • Substance use disorder and sleep: complex pharmacological effects on an underappreciated behavior [at Manfred-Lautenschläger-Hörsal]
Chairs: Lais Berro & Robert Gould (US)
Aida Mohammadkhani (Canada)
Orexin mechanisms regulating sleep and reward
Robert Gould (US)
Progressive sleep alterations following cocaine or oxycodone self-administration in rats
Lais Berro (US)
Methamphetamine-induced sleep impairment: insights from nonhuman primate studies
Vinicius Dokkedal-Silva (Brazil)
Sleep and substance use disorders in South America: evidence from Brazilian studies
Symposium 9 • Towards neural markers of drug addiction: computational approaches in animals and humans [at Fuchs-Petrolub-Festsaal]
Chairs: Miguel Luján & Hedy Kober (US)
Anna Beroun (Poland)
The plasticity of brain circuits processing natural and pharmacological rewards
Miguel Luján (US)
A Bayesian regressor of patterned dopamine release predicts relapse to cocaine
Anna Konova (US)
Suboptimal foraging decisions and involvement of the ventral tegmental area in human opioid addiction
Hedy Kober (US)
A machine-learning based neural marker for craving distinguishes drug users from non-users
16:45-18:15
Parallel symposia
Symposium 10 • Placebo effects: from basic mechanisms to clinical applications [at Aula]
Chairs: Titilola Akintola & Luana Colloca (US)
Matthew Banghart (US)
Descending neural pathways drive placebo antinociception in rodents
Loren Martin (Canada)
Decoding the neural networks of placebo-based learning in rodents
Luana Colloca (US)
A roadmap to understanding human mechanisms of placebo effects
Ulrike Bingel (Germany)
Placebo effects and their applications in clinical practice
Symposium 11 • Lateral habenula roles in approach-avoidance conflict and neuropsychiatric disorders [at Manfred-Lautenschläger-Hörsal]
Chair: Jocelyn M. Richard (US)
Christian Bravo Rivera (Puerto Rico)
Neural circuits mediating reward approach and punishment avoidance conflict
Jocelyn M. Richard (US)
Glutamatergic basal forebrain projections to lateral habenula in aversion-resistant drinking
Steven Shabel (US)
The function of GABA/glutamate co-release in the lateral habenula
Benjamin A. Ely (US)
Habenula developmental trajectories in adolescents
Symposium 12 • Pharmacokinetic and pharmacodynamic determinants of opioid use disorder and their clinical implications [at Fuchs-Petrolub-Festsaal]
Chair: Daniele Caprioli (Italy)
Ginevra D'Ottavio (Italy)
The pharmacokinetic correlates of heroin-taking and their impact on sociability and relapse vulnerability
Nicolas Marie (France)
Role of pharmacokinetics and pharmacodynamics in neuroadaptations induced by opioids
Emilia Lefevre (US)
Interruption of continuous opioid exposure: impact on the mesolimbic dopamine system
Sandra Comer (US)
Pharmacokinetic and pharmacodynamic relationships as they pertain to illicit opioid use and treatment of opioid use disorder in humans
18:30-19:30
FENS Committee on Animals in Research panel discussion [at Aula]
8:30-9:15
Plenary lecture 3 [at Aula]
Patricia Janak (US)
Evaluating & learning from rewards
9:30-11:00
Parallel symposia
Symposium 13 • Stress adaptation vs. maladaptation: Implications for diseases susceptibility and resilience [at Aula]
Chair: Jason Radley (US)
Sarah Ayash (Germany)
Social threat-safety discrimination: a translationally relevant neurobehavioral signature forecasting resilience
Jason Radley (US)
Activity in a prefrontal–periaqueductal gray circuit overcomes behavioral and endocrine features of the passive coping response
Tallie Z. Baram (US)
Shaping of adult threat behaviors by early-life adversity: molecular and circuit mechanisms
Mathias Schmidt (Germany)
Early life adversity can lead to behavioral adaptation in a sex, age and genetic risk factor-dependent manner
Symposium 14 • Incubation of drug craving: a multi-level translational approach [at Manfred-Lautenschläger-Hörsal]
Chair: Muhammad Parvaz (US)
Xuan (Anna) Li (US)
Role of orbitofrontal cortex and associated circuits in incubation of oxycodone craving
Amy Arguello (US)
Adolescent cocaine exposure and time-dependent effects on relapse
Céline Nicolas (France)
Sex differences in cocaine craving : role of the estrous cycle and ovarian hormones
Muhammad Parvaz (US)
Evidence in humans for incubation of cue-reactivity and its down-regulation
Symposium 15 • The impact of fat and sugar-rich diet on adolescent mental health: exploring the association between gut microbiota and brain in animal models [at Fuchs-Petrolub-Festsaal]
Chair: Małgorzata Filip (Poland)
Beatrice Passani (Italy)
Stress-induced maladaptive responses and microbiota changes are attenuated by a healthy diet
John Cryan (Ireland)
Adolescence as a critical window for examining impact of diet on the microbiota-gut-brain axis
Lindsey Schier (US)
Impact of dietary experience early in life on food-motivated behaviors later in life
Małgorzata Filip (Poland)
Maternal dietary patterns and the development of cocaine use disorder in offspring
11:00-11:30
Coffee break [at Katakomben]
11:30-13:00
Parallel symposia
Symposium 16 • New insights into hindbrain regulation of feeding [at Manfred-Lautenschläger-Hörsal]
Chair: Zhi Yi Ong (Australia)
Henning Fenselau (Germany)
Vagal gut-to-hindbrain signaling and appetite control
Zhi Yi Ong (Australia)
Hindbrain catecholaminergic control of feeding behaviours
Giuseppe D’Agostino (UK)
Toward the calm: caudal brainstem circuits as a target of improved appetite and body weight lowering medications
Kate Ellacott (UK)
Hindbrain astrocytes and the regulation of food intake
Symposium 17 • The skin as a stress buffer: mechanisms underpinning the relationship between stress and touch processing [at Fuchs-Petrolub-Festsaal]
Chair: Leah Mayo (Canada)
Claudia Massaccesi (Austria)
The impact of stress and opioid administration on liking and wanting of affective touch
Leah Mayo (Canada)
Endocannabinoid contributions to affective touch in humans with or without trauma exposure
Tracy Bale (US)
A critical window for trauma exposure during adolescence to impact extracellular vesicle proteomics in women
Yvonne Friedrich (Germany)
Affective touch promotes autonomic regulation in preterm infant humans
Symposium 18 • Novel tools and recent advances in the role of brain mu opioid receptors in rewarding and aversive effects of drugs [at Aula]
Chair: Jennifer Bossert (US)
Emmanuel Darcq (France)
Opioid neuronal circuitries in negative and positive affect in knock-in MOR-Cre mice
Jennifer Bossert (US)
Effect of selective lesions of nucleus accumbens MOR-expressing cells on heroin self-administration in male and female rats: a study with novel Oprm1-Cre knock-in rats
Marjorie Levinstein (US)
Unique pharmacodynamic properties of the µ-opioid receptor ligand (S)-methadone
Jordi Bonaventura (Spain)
Mechanistic neuropsychopharmacology of ketamine enantiomers: implications for abuse liability
13:00-15:00
Lunch and Posters [at Katakomben]
15:00-16:30
Parallel symposia
Symposium 19 • Neurocircuits of sensory and emotional pain and their impact in the development of co-morbid symptomatology [at Fuchs-Petrolub-Festsaal]
Chair: Nicolas Massaly (US)
Yarimar Carrasquillo (US)
Circuits for bidirectional pain modulation in the amygdala
Nicolas Massaly (US)
Accumbens-hypothalamus dynorphin circuits in pain negative affect
Ipek Yalcin (France)
Role of basolateral amygdala-anterior cingulate cortex pathway in the comorbidity of chronic pain and mood disorders
Jose Moron-Concepcion (US)
Role of the mesolimbic pathway in pain-induced anhedonia and opioid seeking behavior
Symposium 20 • Stress, trauma and cannabinoids [at Manfred-Lautenschläger-Hörsal]
Chair: Connor Haggarty (US)
Hilary Marusak (US)
Childhood functional brain networks keep the score of prenatal cannabis exposure and trauma during childhood
Raega Mazurka (Canada)
Childhood maltreatment and proximal stress exposure in adulthood are associated with endocannabinoid levels in major depression
Tobias Engl (Germany)
The influence of early life stress on endocannabinoids and alcohol consumption, stress resilience, and their associations in adult mice
Marc Ferger (France)
Endocannabinoid system as a biomarker and pharmacological target for non-suicidal self-injurious behaviour in adolescence
Symposium 21 • Neuronal ensemble mechanisms promoting and suppressing motivated actions [at Aula]
Chair: Eisuke Koya (UK)
Eisuke Koya (UK)
Prefrontal cortex ensemble mechanisms underlying the suppression of cue-evoked food seeking following brief access to environmental enrichment
Mihaela Iordanova (Canada)
Propagating fear across the memory network
Leonie Brebner (Japan)
Dorsal medial prefrontal cortex ensemble recruitment in reward-based associative learning
Hermina Nedelescu (US)
Neuronal ensembles regulating opioid-motivated approach and avoidance behavior
16:45-17:15
Young Investigator Award lecture[at Aula]
Leslie Ramsey (US)
In search of neuronal ensembles that encode volitional social interaction
17:15-18:15
EBPS General Assembly meeting [all are invited at Aula]
19:00-24:00
Social event at Molkenkur Heidelberg
[Buses leave Mannheim between 18:30 and 19:00 from the Mannheim Baroque Palace (Herrenhof) and back from Heidelberg between 23:00 and 24:00]
8:30-9:15
Plenary lecture 4 [at Aula]
Gavan McNally (Australia)
Punishment: how risk and aversion shape our actions and choices
9:30-11:00
Parallel symposia
Symposium 22 • New learning upon the backdrop of prior knowledge schemas [at Aula]
Chairs: Dorothy Tse (UK) & Tomonori Takeuchi (Denmark)
Geoffrey Schoenbaum (US)
Orbitofrontal-hippocampal interactions in generalized cognitive mapping
Tomonori Takeuchi (Denmark)
Brain region networks for the assimilation of new memory into a schema
Melanie Sekeres (Canada)
Memory consolidation and re-organization: a cross-species approach to understanding mPFC-hippocampal neural dynamics
Dorothy Tse (UK)
Novel human spatial schema paradigm
Symposium 23 • Neurocognitive and immune outcomes of co-occurring HIV infection and substance use [at Manfred-Lautenschläger-Hörsal]
Chair: Jacqueline Barker (US)
Mark Namba (US)
Factors influencing the incubation of cocaine craving in EcoHIV-infected mice
Jared Young (US)
Potential for nicotine to improve cognition in HIV-associated neurological disorders via reducing neuroinflammation
Elise Meeder (The Netherlands)
Effects of cannabis use on immune function in people living with HIV
Dionna Williams (US)
Substance use and CNS antiretroviral therapy efficacy: implications for cognitive function in people with HIV
Symposium 24 • Ketones as a potential treatment for Alcohol Use Disorder – insights from preclinical and clinical studies [at Fuchs-Petrolub-Festsaal]
Chairs: Leandro Vendruscolo (US)
Morgane Thomsen (Denmark)
Effects of ketogenic diet and ketone ester supplementation on acute and long-term alcohol withdrawal symptoms in mice
Marta Rodriguez (Spain)
Ketogenic diet reduces alcohol intake in male mice
Leandro Vendruscolo (US)
Preclinical evidence of ketosis-induced reductions in alcohol drinking and metabolism
Cindy Li (US)
Ketone supplementation in alcohol use disorder: effects on brain energetics, alcohol metabolism, and alcohol consumption
11:00-11:30
Coffee break [at Katakomben]
11:30-13:00
Parallel symposia
Symposium 25 • Novel optogenetic tools and their application in behavioral neuroscience [at Aula]
Chairs: Joost Wiskerke & Johan Sköld (Sweden)
Ofer Yizhar (Israel)
Probing the circuits for early-life social behavior with new opsin-GPCRs
Olivia Masseck (Germany)
sDarken - A new family of genetically encoded serotonin sensors
Bastijn van den Boom (The Netherlands)
Therapeutic mechanisms of deep-brain stimulation in a mouse model for compulsivity
Jung Ho Hyun (South Korea)
Tagging and Manipulating neural ensembles to help treat brain illness
Symposium 26 • The German ReCoDe consortium on losing and regaining control over drug intake: from trajectories to mechanisms [at Manfred-Lautenschläger-Hörsal]
Chair: Rainer Spanagel (Germany)
Andreas Heinz (Germany)
Predictors of alcohol consumption trajectories across the lifespan
Karen Ersche (UK)
Habit formation in cocaine addiction
Rainer Spanagel (Germany)
Neurobehavioral profiles of alcohol and cocaine addiction
Lea Zillich (Germany)
Multi-omics translational signatures of alcohol and cocaine addiction
Symposium 27 • Neural representations of tasks and the world supporting learning and decision-making [at Fuchs-Petrolub-Festsaal]
Chairs: Thorsten Kahnt & Avinash Vaidya (US)
Alexandra Keinath (US)
Quantitative comparison of spatial codes within and beyond rodent hippocampus with representational similarity analysis
Shany Grossman (Germany)
Representation learning of task states in the human brain and in artificial networks
Mona Garvert (Germany)
Multi-dimensional cognitive maps adaptively guide reward generalisation
Avinash Vaidya (US)
Neural representation of abstract task structure during generalization
13:15-13:30
Closing remarks [at Aula]
13:30-14:00
EBPS Executive Committee Meeting
(by invitation, including new members)
P1.1 Felippe Amorim (Cambridge, United Kingdom)
Is motivation toward a reward a predictor of dysfunctional behavior?
P1.2 Tara Arbab (Amsterdam, The Netherlands)
Intracranial electrophysiological biomarkers of compulsivity in obsessive-compulsive disorder
P1.3 Priscila Batista Da Rosa (Linköping, Sweden)
The role of microglia in molecular and behavioral alterations after systemic inflammation
P1.4 Lais Berro (, USA)
Effects of suvorexant on methamphetamine self-administration in rhesus monkeys
P1.5 Carla Carratala Ros (Castellon de la Plana, Spain)
Impact of dopamine modulation on the cerebral dopamine neurotrophic factor (CDNF) in nucleus accumbens
P1.6 Silvia Castany Quintana (Linkoping, Sweden)
Lateral habenula activation regulates peripheral and central immune reactivity in aversive states
P1.7 Jonathan Chow (Baltimore, USA)
Avoiding naloxone-induced precipitated withdrawal: a procedure for studying opioid negative reinforcement in rats
P1.8 Xu Ding (Mannheim, Germany)
The EZH2 pathway participates in the neonatal incision-induced exaggeration of incisional pain via microglial activation
P1.9 Jennifer Ellis (Baltimore, MD, USA)
Effects of sex and depressive symptoms on daily withdrawal and craving among persons in medically managed inpatient treatment for opioid use disorder
P1.10 Daiane Engel (Linköping, Sweden)
The type of fat matters in high-fat diet-induced cognitive impairment in mice
P1.11 Harold Haun (Chapel Hill, NC, USA)
Septo-hypothalamic nociceptin/orphanin-fq modulation of binge-like alcohol consumption
P1.12 Liubov Kalinichenko (Erlangen, Germany)
Neutral sphingomyelinase controls the comorbidity trias of alcohol abuse, major depression and bone defects in females
P1.13 Sara Kroll (Zurich, Switzerland)
Basal endocannabinoid plasma levels in chronic non-medical prescription opioid users and its link social exclusion
P1.14 Brittany Kuhn (Charleston, South Carolina, USA)
Multi-symptomatic approach reveals distinct behavioral profiles and neuronal correlates of heroin vulnerability versus resiliency
P1.15 Gisela Lazzarino (Linköping, Sweden)
Characterization of melanocortin 4 receptor-expressing neurons in the lateral stripe of the striatum
P1.16 Tsen Vei Lim (Cambridge, United Kingdom)
Impaired in different ways: dissociable reinforcement learning deficits in chronic cocaine, cannabis, and alcohol users
P1.17 Rachel Luba (Brooklyn, NY, USA)
Evaluating the abuse potential of lenabasum, a mixed CB1/CB2 cannabinoid agonist
P1.18 Natalia Malikowska-Racia (Krakow, Poland)
Effects of free food availability and amphetamine administration on effort-based choice in rats
P1.19 Elena Martín-González (Almería, Spain)
Diffusion MRI reveals microstructural brain alterations in compulsive rats selected by schedule induced polydipsia
P1.20 Kate Peters (Brighton, United Kingdom)
Prefrontal cortex ensemble mechanisms in suppressing cue-evoked food seeking following environmental enrichment
P1.21 Eugenia Poh (Amsterdam, The Netherlands)
Characterizing dopamine’s encoding of future rewards and motor function in discrete striatal subregions
P1.22 Agnieszka Potasiewicz (Krakow, Poland)
The effects of the alpha7 nAChR PAMs on rats’ social play behavior in the neurodevelopmental model of schizophrenia
P1.23 Marina Reguilón Romero (Valencia, Spain)
Behavioral characterization of vicarious social defeat in adolescent female mice
P1.24 Matthew Rich (Piscataway, USA)
A rodent model to investigate the physiological mechanisms of fear-dependent cocaine seeking
P1.25 Valeria Tarmati (Roma, Italy)
Conditioned cues associated with rewarding or aversive stimuli can induce the same or opposite responses by the paraventricular thalamus depending on individuals’ genotype
P1.26 Zuzana Vaverkova (Falmer, Brighton, United Kingdom)
Enhanced activity of parvalbumin neurons and protein phosphatase calcineurin in mesocrotciolimbic brain areas following extinction of food-memory
P1.27 Emily Ah-Yen (Montreal,, Canada)
The effects of chemogenetic and pharmacological inhibition of the anterior paraventricular nucleus of the thalamus on heroin seeking in abstinent rats
P1.28 Isis Alonso-Lozares (Amsterdam, The Netherlands)
The role of Lateral Hypothalamus GABA neurons in the formation and recall of alcohol memories
P1.29 Hanna Belschner (Mannheim, Germany)
Cell type-specific multi-omics analysis of cocaine use disorder in the human caudate nucleus
P1.30 Paula Berbegal Sáez (Barcelona, Spain)
The time of your life: clock gene Bmal1 has an important role in natural reward seeking behavior
P1.31 Catarina Borges (Montreal, Canada)
The effect of chemogenetic activation of the pPVT on food deprivation-induced relapse to heroin seeking after punishment-imposed abstinence, in male and female rats
P1.32 Kanat Chanthongdee (Linköping, Sweden)
Role of Prdm2 through the prefrontal projection in stress-induced reinstatement of alcohol seeking: an epigenetic mechanism with translational potential
P1.33 Daria Chestnykh (Erlangen, Germany)
Sphingolipid neurobiology of psychosis and its treatment in rats
P1.34 Agata Cieślik (Krakow, Poland)
Understanding alcohol addiction: how sensitivity to negative and positive feedback affects the drinking behavior in rats
P1.35 Carles Colom Rocha (Palma, Spain)
Adolescent ethanol exposure increased voluntary consumption during adulthood in male and female rats: Exploring the beneficial effects of cannabidiol or ketamine
P1.36 Adam Prus (Marquette, MI, USA)
Discriminative stimulus properties of gabapentin in rats
P1.37 Harashdeep Deol (Mississauga, Canada)
Social modulation of pain in drug-naïve cohabitants of mice administered chronic morphine
P1.38 Stephanie Desrochers (Hanover, NH, USA)
Distinct populations of 5-HT1BRs in the brain modulate reward hedonics compared to motivation and impulse control
P1.39 Mariana Duque Quintero (Amsterdam, The Netherlands)
Local and global corticostriatal manipulations differentially affect distinct forms of compulsive behavior
P1.40 Christian Edvardsson (Gothenburg, Sweden)
GLP-1 receptors in the lateral septum regulate intake and reward of alcohol in rodents of both sexes
P1.41 Lauri Elsilä (Helsinki, Finland)
Lysergic acid diethylamide for prevention of withdrawal-induced relapse in alcohol seeking of group-housed female mice – a pilot study
P1.42 Miguel Farinha-Ferreira (Lisboa, Portugal)
Tripping on dosing: acute and lasting dose-dependent effects of psilocybin on functional connectivity and affective behavior
P1.43 Princess Felix (Ann Arbor, MI, USA)
Elucidating the role of glucocorticoid receptors in the inhibitory control of cue-motivated behaviors
P1.44 Lizz Fellinger (Amsterdam, The Netherlands)
Regional striatal dopamine signaling during spontaneous movement reflects intrinsic motivation
P1.45 Claudia Fornari (Bordeaux, France)
Sexual dimorphism of posterior insular cortex function in persistent alcohol drinking despite aversion in mice
P1.46 Marion Friske (Mannheim, Germany)
Gene expression signatures in AUD – a translational approach
P1.47 Caspar Geissler (Hamburg, Germany)
Aversive learning following regular opioid use
P1.48 Brianna George (Winston Salem, NC, USA)
Adolescent social isolation drives increased heroin vulnerability and dysregulates the dopamine system
P1.49 Francesco Giannone (Mannheim, Germany)
Generalized habitual tendencies in alcohol dependent rats
P1.50 Joanna Golebiowska (Kraków, Poland)
Rats with life-long genetic depletion of brain serotonin demonstrate decrease 50-kHz “happy calls” following amphetamine administration
P1.51 Macarena González Portilla (València, Spain)
Oleoylethanolamide effects on alcohol self-administration: exploring gene expression changes in the striatum and hippocampus
P1.52 Michal Graczyk (Cambridge, United Kingdom)
Age of onset of cocaine use is associated with microstructural brain white matter changes in Cocaine Use Disorder patients
P1.53 Connor Haggarty (Chicago, IL, USA)
MDMA enhances cortical responses to emotional faces
P1.54 Kimberly Holter (Winston-Salem, NC, USA)
17β-estradiol deprivation in female rats alters NMDAR function and antipsychotic response
P1.55 Cristina Izquierdo Luengo (Madrid, Spain)
Neurobiological consequences of adolescent exposure to AB-FUBINACA, a synthetic cannabinoid found in Spice/K2 preparations, in male and female mice
P1.56 Urte Jasinskyte (Vilnius, Lithuania)
Ketamine changes spontaneous and induced brain activity in awake mice
P1.57 Jordi Jornet-Plaza (Palma, Spain)
Characterization of the antidepressant-like response of ketamine in adolescent rats while including sex as a biological variable
P1.58 Eloise Kuijer (Bath, United Kingdom)
Electrophysiological analysis of kappa opioid receptor activation in mouse paraventricular thalamus
P1.59 Anna Maria Borruto (Linköping, Sweden)
A trauma-sensitive neural pathway drives pain-related anxiety in female mice
P1.60 Leon Höglund (Linköping, Sweden)
The role of EZH2 in compulsive alcohol use
P1.61 Allison McDonald (Amsterdam, The Netherlands)
Alcohol use despite negative consequences: Identifying associated brain circuits in a rat model
P1.62 Cagdas Türkmen (Mannheim, Germany)
Is childhood maltreatment associated with changes in brain volume and cortical thickness in adults with alcohol use disorder? The role of the type and timing of maltreatment
P2.1 Mia Langguth (Stanmore, Australia)
The lateral septum is associated with fleeing social contact in mice – but is this effect social-specific?
P2.2 Bixuan Lin (Kensington, Australia)
Dopamine binding in dorsal striatum during punishment learning
P2.3 Cody Lis (20 Penn St, Maryland, USA)
A model of social coordination in rats
P2.4 Cassandra Ma (Kensington, Australia)
Cortico-striatal pathway differentially mediates cued punishment expression and fear to the cue in a conditioned punishment task
P2.5 Claudia Marchetti (Rome, Italy)
Role of microglia on synaptic plasticity mechanisms underlying persistent cocaine-associated maladaptive memories
P2.6 Madison Marcus (Richmond, VA, USA)
Extended access cocaine or fentanyl self-administration and withdrawal does not increase drug choice over an alternative negative reinforcer in male and female rats
P2.7 Andrea Martinez Verdu (Castellon, Spain)
Individual differences in running wheel performance are related to preferences for active reinforcers: role of dopamine-related markers in nucleus accumbens
P2.8 Claudia Massaccesi (, Austria)
Neurobiology and state-dependency of human social affiliation: behavioural, pharmacological, and neurophysiological insights
P2.9 Elina Nagaeva (Helsinki, Finland)
Somatostatin-positive neurons in the ventral tegmental area affect morphine sensitization and stress-related behaviour
P2.10 Régulo Olivares García (Castellón de la Plana, Spain)
Preference for active versus sedentary sources of reinforcement: role of the dopaminergic system and the role of different types of previous exercise
P2.11 Manuela Olmedo Córdoba (Almería, Spain)
Identifying factors associated with a vulnerable population to compulsive alcohol drinking: pathological gambling and social dominance
P2.12 Virginia Opara (Montreal, Canada)
Optogentic modulation of VTA DA neurons and its terminals regulates learning through aversive prediction error
P2.13 Zhi Yi Ong (, Australia)
Role of glucagon-like peptide-1 receptor signalling in the dorsal lateral septum on alcohol intake behaviours
P2.14 Kimberly Papastrat (Baltimore, Maryland, USA)
A socio-sensory mechanism buffering drug craving
P2.15 Sara Pezza (Rome, Italy)
Effect of social choice-induced voluntary abstinence on incubation of methamphetamine craving and AMPA receptor expression in nucleus accumbens core
P2.16 Luise Pickenhan (Cambridge, United Kingdom)
Probing the habitual basis of dysfunctional checking in a rodent analogue of compulsive-like checking in obsessive-compulsive disorder
P2.17 Bethany Pierce (Winston-Salem, NC, USA)
The effects of full and partial opioid agonists and antagonists on sleep and quantitative EEG activity
P2.18 Ieva Poceviciute (Vilnius, Lithuania)
Scopolamine animal model of memory impairment
P2.19 Veronika Pohorala (Mannheim, Germany)
The effects of chronic cocaine self-administration on mGluR2 expression
P2.20 Simran Rehal (Toronto, Canada)
Investingating the role of the ventral anterior cingulate cortext in placebo analgesia
P2.21 Rhiannon Robke (Amsterdam, The Netherlands)
A novel TPH2-iCre transgenic rat line enables selective manipulation of the serotonin system during locomotor, compulsive, and reinforced behavior
P2.22 Marta Rodriguez (, Spain)
Effect of ketogenic diet on prepulse inhibition response in female mice subjected to social stress
P2.23 Lorena Roselló-Jiménez (Castelló de la Plana, Spain)
Ethanol binge-like drinking in C57BL/6J mice: evaluation of c-fos expression in the hypothalamic arcuate nucleus and nucleus accumbens
P2.24 Annika Schäfer (Helsinki, Finland)
BDNF-mediated plasticity underlying development to benzodiazepine tolerance
P2.25 Brendan Sharvin (Cork, Ireland)
Neurobehavioral effects at adulthood induced by translatable early life perturbations to the microbiome
P2.26 Ariádne Silva (Florianópolis, Brazil)
Brilliant blue g, a p2x7 purinergic receptor antagonist, improves memory and alleviates anxiety and depression symptoms in a streptozotocin-induced Alzheimer’s disease model in mice
P2.27 William Silver (Cambridge, United Kingdom)
On value and probability: a computational re-evaluation of risky decision-making in cocaine use disorder
P2.28 Oliver Tan (Camperdown, Australia)
The vasopressin V1a receptor represents a novel therapeutic target for the treatment of social dysfunction
P2.29 Marc Ten Blanco (Pozuelo de Alarcón, Spain)
Inter-individual differences in the extinction of fear memories: a multifactorial study with male and female mice
P2.30 Sanne Toivainen Eloff (Linköping, Sweden)
Sex differences in alcohol related behaviors
P2.31 Simone Tonetto (Frederiksberg, Denmark)
Nutritional ketosis as treatment for alcohol withdrawal symptoms
P2.32 Martin Trøstheim (Oslo, Norway)
Cold pain sensitivity in patients receivingopioid agonist treatmentfor opioid use disorder: preliminary results from a systematic review and meta-analysis
P2.33 Suzanne Truong (Vienna, Austria)
Neuroendocrine dynamics of positive human-animal interactions: the role of oxytocin, dopamine and opioids
P2.34 Madeline Van Fossen (Marquette, Michigan, USA)
Assessment of dextromethorphan as a treatment for compulsive behavioral disorders using the schedule-induced polydipsia paradigm in rats
P2.35 Felice Veen (Amsterdam, The Netherlands)
Differential population dynamics in the medial prefrontal cortex during action control
P2.36 Lars Wilmes (Cork, Ireland)
Behavioural outcomes following early life stress: focus on the role of the microbiome-gut-brain axis in resilience and vulnerability
P2.37 Livia Wilod Versprille (Cambridge, United Kingdom)
Dissociable effects of methylphenidate and atomoxetine on visual signal detection in rats
P2.38 Kacper Witek (Kraków, Poland)
Obesity-inducing diet alters behavioral status and GABAB receptor expression in rat obesity phenotypes
P2.39 Casper Wolf (Nijmegen, The Netherlands)
The residual effects of GHB use and GHB-induced comas on visuospatial working memory performance in outbred rats
P2.40 Soami Filippo Zenoni (Rome, Italy)
The role of dorsal raphe mglur5 containing neurons on incubation of metamhetamine craving
P2.41 Marijke Achterberg (Utrecht, The Netherlands)
Chemogenetic activation of VTA-dopamine neurons affects operant responding for but not expression of social play in young rats
P2.42 Eric Augier (Linköping, Sweden)
Social status matters: subordinate rats choose oxycodone over social interaction compared to dominant counterparts
P2.43 Cecilia Bergeria (Baltimore, MD, USA)
Within-subject, double-blind human laboratory evaluation of cannabidiol on opioid-induced analgesia and subjective effects
P2.44 Aurelijus Burokas (Vilnius, Lithuania)
Microbiota transplantation from autism spectrum disorder patients: the route of transfer maters for its effect on adult mice behaviour
P2.45 Simona Cabib (Roma, Italy)
Sensitization to adult stress and increased hyperpolarization-activated current (Ih) density in dopamine neurons of the ventral tegmental area are fostered by the neonatal disruption of attachment with the caregiver in female mice only
P2.46 Simon Barak Caine (Belmont, Massachusetts, USA)
Sprague Dawley rats from different vendors vary in the modulation of prepulse inhibition of startle (PPI) by dopamine, acetylcholine, and glutamate drugs
P2.47 Andrea Coppola (Linköping, Sweden)
The effects of prolonged social isolation in adulthood on alcohol-related behaviors in female and male Wistar rats
P2.48 Johan Sköld (, Sweden)
Melanocortin 4 receptor-expressing neurons in the lateral stripe of the striatum: response to rewarding and aversive stimuli and relationship with dopamine release
P2.49 Rebecca Hofford (Winston-Salem, NC, USA)
Disruption of the gut microbiome influences medial prefrontal cortex-dependent behaviors and protein expression in adolescent rats
P2.50 Andrew Huhn (Baltimore, Maryland, USA)
Dual orexin-receptor antagonist effects on biological and patient-reported stress during opioid withdrawal
P2.51 Jolanta Kotlińska (Lublin, Poland)
Neonatal maternal separation induces sex-specific differences in the level of hippocampal amino acids in adult rats: impact on cognitive behavior
P2.52 Michela Marinelli (Austin, TX, USA)
A novel small molecule inhibitor of PKC epsilon blocks hyperalgesia induced by opioid withdrawal
P2.53 Inmaculada Pereda (Madrid, Spain)
MeCP2 Duplication Syndrome, a mouse model to understand the molecular mechanisms of this rare neurodevelopmental disorder
P2.54 John Salamone (Storrs, Connecticut, USA)
Assessment of novel atypical dopamine transport inhibitors with tests of effort-based choice in rats
P2.55 Rainer Schwarting (Marburg, Germany)
Acute anxiogenic effects of escitalopram do not lead to prominent alterations of amphetamine-induced 50-kHz calling and social approach evoked by ultrasound playback in the rat
P2.56 Magdalena Sustkova (Prague 10, Czech Republic)
Ghrelin/GHS-R1A antagonism in memory test and its effects on central molecular signaling involved in addiction in rats
P2.57 Susannah Walker (Liverpool, United Kingdom)
Daily dynamic stroking touch modulates stress resilience in rats exposed to chronic mild stress
P2.58 Akseli Graf (Mannheim, Germany)
Axonal oxytocin release in the paraventricular nucleus of the thalamus impairs social memory
P2.59 Lorenzo Mattioni (Mainz, Germany)
Early life adversity and the impact of glucocorticoids on NG2-glia: a potential mechanism for stress-related psychiatric disorders
P2.60 Dersu Ozdemir (Strasbourg, France)
Implication of habenular neurons expressing mu opioid receptors in negative affect associated with naloxone precipitated morphine withdrawal
P2.61 Olga Rodríguez Borillo (Castellón, Spain)
Intracranial clenbuterol administration facilitates extinction of pavlovian conditioned memories associated with cocaine exposure
[title]
[authorship]
[text]